3136 : 2-(3-{[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3136 |
| Name | 2-(3-{[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)-2-methylpropanoic acid |
| smile | COC1=CC=C(C(N2C(=C(C3=CC(=CC=C23)OC(F)(F)F)CC2=CC=CC(=C2)OC(C(O)=O)(C)C)C)=O)C=C1 |
| weight | 542 |
| scaffold ID | 132 |
| scaffold smile | O=C(c1ccccc1)n1cc(Cc2ccccc2)c2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3136 | 2-(3-{[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)-2-methylpropanoic acid | 0.006 |
Scaffold Activities Statistic