3164 : (2R)-2-(4-chloro-3-{[1-(6-methoxy-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3164 |
| Name | (2R)-2-(4-chloro-3-{[1-(6-methoxy-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid |
| smile | COC1=CC=C2C(N3C(=C(C4=CC(=CC=C34)OC(F)(F)F)CC3=CC(=CC=C3Cl)O[C@@H](C(O)=O)C)C)=NOC2=C1 |
| weight | 575 |
| scaffold ID | 1617 |
| scaffold smile | c1c(Cc2ccccc2)c2ccccc2n1-c1noc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3164 | (2R)-2-(4-chloro-3-{[1-(6-methoxy-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid | 0.003 |
Scaffold Activities Statistic