3166 : (2S)-2-(3-{[1-(6-methoxyquinolin-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3166 |
| Name | (2S)-2-(3-{[1-(6-methoxyquinolin-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid |
| smile | COC1=CC=C2N=CC(N3C(=C(C4=CC(=CC=C34)OC(F)(F)F)CC3=CC=CC(=C3)O[C@H](C(O)=O)C)C)=CC2=C1 |
| weight | 551 |
| scaffold ID | 1616 |
| scaffold smile | c1c(Cc2ccccc2)c2ccccc2n1-c1cnc2ccccc2c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3166 | (2S)-2-(3-{[1-(6-methoxyquinolin-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl}phenoxy)propanoic acid | 0.049 |
Scaffold Activities Statistic