3168 : (2S)-2-(3-chloro-5-{[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]oxy}phenoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3168 |
| Name | (2S)-2-(3-chloro-5-{[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]oxy}phenoxy)propanoic acid |
| smile | C[C@@H](C(O)=O)OC1=CC(=CC(=C1)OC1=C(N(C2=CC=C(C=C12)OC(F)(F)F)C1=NOC2=CC(=CC=C12)Cl)C)Cl |
| weight | 581 |
| scaffold ID | 1251 |
| scaffold smile | c1c(Oc2ccccc2)c2ccccc2n1-c1noc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3168 | (2S)-2-(3-chloro-5-{[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]oxy}phenoxy)propanoic acid | 0.114 |
Scaffold Activities Statistic