3181 : (2S)-2-{[2-oxo-3-(propan-2-yl)-5,7-dipropyl-2,3-dihydro-1,3-benzoxazol-6-yl]oxy}-2-[4-(propan-2-yl)phenyl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3181 |
| Name | (2S)-2-{[2-oxo-3-(propan-2-yl)-5,7-dipropyl-2,3-dihydro-1,3-benzoxazol-6-yl]oxy}-2-[4-(propan-2-yl)phenyl]acetic acid |
| smile | CCCC1=CC2N(C(OC=2C(=C1O[C@@H](C1=CC=C(C(C)C)C=C1)C(O)=O)CCC)=O)C(C)C |
| weight | 454 |
| scaffold ID | 113 |
| scaffold smile | O=c1[nH]c2ccc(OCc3ccccc3)cc2o1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3181 | (2S)-2-{[2-oxo-3-(propan-2-yl)-5,7-dipropyl-2,3-dihydro-1,3-benzoxazol-6-yl]oxy}-2-[4-(propan-2-yl)phenyl]acetic acid | 0.14 |
Scaffold Activities Statistic