3189 : 1-(4-tert-butylphenyl)-3-{4-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3189 |
| Name | 1-(4-tert-butylphenyl)-3-{4-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid |
| smile | CC(C1=CC=C(N2C(=C(C3=CC=CN=C23)OC2=CC=C(C3=CC(C(F)(F)F)=CN3)C=C2)C(O)=O)C=C1)(C)C |
| weight | 520 |
| scaffold ID | 1465 |
| scaffold smile | c1c[nH]c(-c2ccc(Oc3cn(-c4ccccc4)c4ncccc34)cc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3189 | 1-(4-tert-butylphenyl)-3-{4-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid | 0.034 |
Scaffold Activities Statistic