3193 : 1-(4-tert-butylphenyl)-6-chloro-3-{3-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3193 |
| Name | 1-(4-tert-butylphenyl)-6-chloro-3-{3-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid |
| smile | CC(C1=CC=C(N2C(=C(C3=CC=C(N=C23)Cl)OC2=CC=CC(C3=CC(C(F)(F)F)=CN3)=C2)C(O)=O)C=C1)(C)C |
| weight | 554 |
| scaffold ID | 814 |
| scaffold smile | c1c[nH]c(-c2cccc(Oc3cn(-c4ccccc4)c4ncccc34)c2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3193 | 1-(4-tert-butylphenyl)-6-chloro-3-{3-[4-(trifluoromethyl)-1H-pyrrol-2-yl]phenoxy}-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid | 0.095 |
Scaffold Activities Statistic