3203 : 1-(4-tert-butylphenyl)-5-[(4-chloro-1H-pyrrol-2-yl)oxy]-3-[3-(trifluoromethyl)phenoxy]-1H-indole-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3203 |
| Name | 1-(4-tert-butylphenyl)-5-[(4-chloro-1H-pyrrol-2-yl)oxy]-3-[3-(trifluoromethyl)phenoxy]-1H-indole-2-carboxylic acid |
| smile | CC(C1=CC=C(N2C(=C(C3=CC(=CC=C23)OC2=CC(=CN2)Cl)OC2=CC=CC(C(F)(F)F)=C2)C(O)=O)C=C1)(C)C |
| weight | 569 |
| scaffold ID | 599 |
| scaffold smile | c1c[nH]c(Oc2ccc3c(c2)c(Oc2ccccc2)cn3-c2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3203 | 1-(4-tert-butylphenyl)-5-[(4-chloro-1H-pyrrol-2-yl)oxy]-3-[3-(trifluoromethyl)phenoxy]-1H-indole-2-carboxylic acid | 0.002 |
Scaffold Activities Statistic