3316 : (5E)-5-[[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-4,5,6,7-tetrahydro-1-benzofuran-2-yl]methylidene]-1,3-thiazolidine-2,4-dione
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3316 |
| Name | (5E)-5-[[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-4,5,6,7-tetrahydro-1-benzofuran-2-yl]methylidene]-1,3-thiazolidine-2,4-dione |
| smile | S1C(NC(/C/1=C\C1=CC2=C(CCCC2C2C=CC3=C(C=2)C(C)(C)CCC3(C)C)O1)=O)=O |
| weight | 436 |
| scaffold ID | 1544 |
| scaffold smile | O=C1NC(=O)C(=Cc2cc3c(o2)CCCC3c2ccc3c(c2)CCCC3)S1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 3316 | (5E)-5-[[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-4,5,6,7-tetrahydro-1-benzofuran-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | 0.02 |
Scaffold Activities Statistic