3403 : (1R,2R)-1,2-dimethyl-2-((1E,3E)-4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)penta-1,3-dienyl)cyclopropanecarboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3403 |
| Name | (1R,2R)-1,2-dimethyl-2-((1E,3E)-4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)penta-1,3-dienyl)cyclopropanecarboxylic acid |
| smile | C1(C)(C)C2=C(C=C(/C(/C)=C/C=C/[C@@]3([C@](C)(C(=O)O)C3)C)C(C)=C2)C(C)(C)CC1 |
| weight | 381 |
| scaffold ID | 1457 |
| scaffold smile | C(C=CC1CC1)=Cc1ccc2c(c1)CCCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 3403 | (1R,2R)-1,2-dimethyl-2-((1E,3E)-4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)penta-1,3-dienyl)cyclopropanecarboxylic acid | 0.139 |
Scaffold Activities Statistic