3540 : 2-(4-{[(3S)-3-[(2,4-dichlorophenyl)carbamoyl]-1,2,3,4-tetrahydroisoquinolin-2-yl]methyl}-2-methylphenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3540 |
| Name | 2-(4-{[(3S)-3-[(2,4-dichlorophenyl)carbamoyl]-1,2,3,4-tetrahydroisoquinolin-2-yl]methyl}-2-methylphenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)CN1CC2=CC=CC=C2C[C@H]1C(NC1=CC=C(C=C1Cl)Cl)=O |
| weight | 499 |
| scaffold ID | 808 |
| scaffold smile | O=C(Nc1ccccc1)C1Cc2ccccc2CN1Cc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3540 | 2-(4-{[(3S)-3-[(2,4-dichlorophenyl)carbamoyl]-1,2,3,4-tetrahydroisoquinolin-2-yl]methyl}-2-methylphenoxy)acetic acid | 2.5 |
Scaffold Activities Statistic