3600 : 2-(4-{[4-(4-methoxyphenyl)-5-[4-phenyl-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3600 |
| Name | 2-(4-{[4-(4-methoxyphenyl)-5-[4-phenyl-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid |
| smile | COC1=CC=C(C2N=C(SC=2C2=CC=C(C(C(F)(F)F)=C2)C2=CC=CC=C2)COC2=CC=C(C(=C2)C)OCC(O)=O)C=C1 |
| weight | 606 |
| scaffold ID | 13 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccc(-c4ccccc4)cc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3600 | 2-(4-{[4-(4-methoxyphenyl)-5-[4-phenyl-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic