3612 : 2-fluoro-2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-(propan-2-yl)phenoxy}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3612 |
| Name | 2-fluoro-2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-(propan-2-yl)phenoxy}acetic acid |
| smile | CC(C1=CC(=CC=C1OC(C(O)=O)F)SCC1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C)C |
| weight | 500 |
| scaffold ID | 64 |
| scaffold smile | c1nc(-c2ccccc2)sc1CSc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3612 | 2-fluoro-2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-(propan-2-yl)phenoxy}acetic acid | 0.735 |
Scaffold Activities Statistic