3689 : 2-[2-methyl-4-({4-[6-(propan-2-yloxy)pyridin-3-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3689 |
| Name | 2-[2-methyl-4-({4-[6-(propan-2-yloxy)pyridin-3-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid |
| smile | CC(OC1=CC=C(C2N=C(SC=2C2=CC=C(C=C2)OC(F)(F)F)COC2=CC=C(C(=C2)C)OCC(O)=O)C=N1)C |
| weight | 575 |
| scaffold ID | 8 |
| scaffold smile | c1ccc(OCc2nc(-c3cccnc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3689 | 2-[2-methyl-4-({4-[6-(propan-2-yloxy)pyridin-3-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid | 10.0 |
Scaffold Activities Statistic