3744 : 2-ethoxy-3-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenyl)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3744 |
| Name | 2-ethoxy-3-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenyl)propanoic acid |
| smile | CCOC(C(O)=O)CC1=CC=C(C=C1)OCC1=NC(=C(C2=CC=C(C(F)(F)F)C=C2)S1)C1=CC=C(C=C1)OC |
| weight | 558 |
| scaffold ID | 12 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3744 | 2-ethoxy-3-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenyl)propanoic acid | 1.09 |
Scaffold Activities Statistic