3943 : 2-[4-({3-[3-chloro-4-(trifluoromethoxy)phenyl]-1,2,4-thiadiazol-5-yl}methoxy)-2-methylphenoxy]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3943 |
| Name | 2-[4-({3-[3-chloro-4-(trifluoromethoxy)phenyl]-1,2,4-thiadiazol-5-yl}methoxy)-2-methylphenoxy]-2-methylpropanoic acid |
| smile | CC1=CC(=CC=C1OC(C(O)=O)(C)C)OCC1=NC(C2=CC=C(C(=C2)Cl)OC(F)(F)F)=NS1 |
| weight | 503 |
| scaffold ID | 529 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)ns2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3943 | 2-[4-({3-[3-chloro-4-(trifluoromethoxy)phenyl]-1,2,4-thiadiazol-5-yl}methoxy)-2-methylphenoxy]-2-methylpropanoic acid | 0.097 |
Scaffold Activities Statistic