3975 : 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-(3,4-dichlorophenoxy)acetamido}propyl)phenoxy]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3975 |
| Name | 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-(3,4-dichlorophenoxy)acetamido}propyl)phenoxy]-2-methylpropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC(=C1)CCCN(C1=CC=CC(=C1C1CC1)C1=NOC=N1)C(COC1=CC=C(C(=C1)Cl)Cl)=O)C |
| weight | 625 |
| scaffold ID | 726 |
| scaffold smile | O=C(COc1ccccc1)N(CCCc1ccccc1)c1cccc(-c2ncon2)c1C1CC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 3975 | 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-(3,4-dichlorophenoxy)acetamido}propyl)phenoxy]-2-methylpropanoic acid | 0.23 |
Scaffold Activities Statistic