4377 : 2-[(1S)-5-{2-[2-(4-ethylphenyl)-1,5-dimethyl-1H-imidazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4377 |
| Name | 2-[(1S)-5-{2-[2-(4-ethylphenyl)-1,5-dimethyl-1H-imidazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | CCC1=CC=C(C2=NC(=C(N2C)C)CCOC2=CC=C3[C@@H](CCC3=C2)CC(O)=O)C=C1 |
| weight | 419 |
| scaffold ID | 352 |
| scaffold smile | c1nc(-c2ccccc2)[nH]c1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4377 | 2-[(1S)-5-{2-[2-(4-ethylphenyl)-1,5-dimethyl-1H-imidazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid | 0.347 |
Scaffold Activities Statistic