4382 : 2-[(1S)-5-{2-[2-(4-methoxyphenyl)-1,4-dimethyl-1H-imidazol-5-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4382 |
| Name | 2-[(1S)-5-{2-[2-(4-methoxyphenyl)-1,4-dimethyl-1H-imidazol-5-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | COC1=CC=C(C2=NC(=C(N2C)CCOC2=CC=C3[C@@H](CCC3=C2)CC(O)=O)C)C=C1 |
| weight | 421 |
| scaffold ID | 352 |
| scaffold smile | c1nc(-c2ccccc2)[nH]c1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4382 | 2-[(1S)-5-{2-[2-(4-methoxyphenyl)-1,4-dimethyl-1H-imidazol-5-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid | 0.086 |
Scaffold Activities Statistic