4431 : (2s,5s)-2-methyl-5-{4-[2-(4-methylphenyl)-5-(trifluoromethyl)-1,3-oxazol-4-yl]butyl}-1,3-dioxane-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4431 |
| Name | (2s,5s)-2-methyl-5-{4-[2-(4-methylphenyl)-5-(trifluoromethyl)-1,3-oxazol-4-yl]butyl}-1,3-dioxane-2-carboxylic acid |
| smile | CC1=CC=C(C2OC(C(F)(F)F)=C(N=2)CCCC[C@@H]2CO[C@](C(O)=O)(OC2)C)C=C1 |
| weight | 427 |
| scaffold ID | 376 |
| scaffold smile | c1oc(-c2ccccc2)nc1CCCCC1COCOC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4431 | (2s,5s)-2-methyl-5-{4-[2-(4-methylphenyl)-5-(trifluoromethyl)-1,3-oxazol-4-yl]butyl}-1,3-dioxane-2-carboxylic acid | 3.0 |
Scaffold Activities Statistic