4435 : 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4435 |
| Name | 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid |
| smile | OC(CC1=CC=CC2=C(C=CC=C12)NCC1=CC=CC(C2=C(C=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1)=O |
| weight | 577 |
| scaffold ID | 548 |
| scaffold smile | c1ccc(Cc2cnc3ccccc3c2-c2cccc(CNc3cccc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4435 | 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid | 0.084 |
Scaffold Activities Statistic