4472 : (2s,5s)-2-methyl-5-[(4-{2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-1,3-dioxane-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4472 |
| Name | (2s,5s)-2-methyl-5-[(4-{2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-1,3-dioxane-2-carboxylic acid |
| smile | CC1=CC=C(C2OC(=C(N=2)CCOC2=CC=C(C=C2)C[C@@H]2CO[C@](C(O)=O)(OC2)C)C)C=C1 |
| weight | 452 |
| scaffold ID | 734 |
| scaffold smile | c1oc(-c2ccccc2)nc1CCOc1ccc(CC2COCOC2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4472 | (2s,5s)-2-methyl-5-[(4-{2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-1,3-dioxane-2-carboxylic acid | 1.385 |
Scaffold Activities Statistic