4580 : 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4580 |
| Name | 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetic acid |
| smile | CC1OC(C2=CC=C(C3=CC=CC=C3)C=C2)=NC=1CCOC1=CC=C2C(C(=C(N2C(C2=CC=C(C=C2)Cl)=O)C)CC(O)=O)=C1 |
| weight | 605 |
| scaffold ID | 1428 |
| scaffold smile | O=C(c1ccccc1)n1ccc2cc(OCCc3coc(-c4ccc(-c5ccccc5)cc4)n3)ccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4580 | 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetic acid | 40000.0 |
Scaffold Activities Statistic