4582 : methyl 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetate
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4582 |
| Name | methyl 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetate |
| smile | COC(CC1=C(N(C2=CC=C(C=C12)OCCC1N=C(C2=CC=C(C3=CC=CC=C3)C=C2)OC=1C)C(C1=CC=C(C=C1)Cl)=O)C)=O |
| weight | 619 |
| scaffold ID | 1428 |
| scaffold smile | O=C(c1ccccc1)n1ccc2cc(OCCc3coc(-c4ccc(-c5ccccc5)cc4)n3)ccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4582 | methyl 2-[1-(4-chlorobenzoyl)-2-methyl-5-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}-1H-indol-3-yl]acetate | 20000.0 |
Scaffold Activities Statistic