4603 : 3-[4-({2-amino-6-[4-(furan-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4603 |
| Name | 3-[4-({2-amino-6-[4-(furan-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC=C1)CC1=CC=C(C=C1)OC1=CC(N2CCN(CC2)CC2OC=CC=2)=NC(=N1)N |
| weight | 530 |
| scaffold ID | 216 |
| scaffold smile | c1coc(CN2CCN(c3cc(Oc4ccc(CCOc5ccccc5)cc4)ncn3)CC2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4603 | 3-[4-({2-amino-6-[4-(furan-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid | 5.01 |
Scaffold Activities Statistic