4604 : 3-[4-({2-amino-6-[4-(4-propylbenzoyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4604 |
| Name | 3-[4-({2-amino-6-[4-(4-propylbenzoyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid |
| smile | CCCC1=CC=C(C(N2CCN(C3=CC(=NC(=N3)N)OC3=CC=C(C=C3)CC(C(O)=O)(OC3=CC=CC=C3)C)CC2)=O)C=C1 |
| weight | 596 |
| scaffold ID | 215 |
| scaffold smile | O=C(c1ccccc1)N1CCN(c2cc(Oc3ccc(CCOc4ccccc4)cc3)ncn2)CC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4604 | 3-[4-({2-amino-6-[4-(4-propylbenzoyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid | 50.0 |
Scaffold Activities Statistic