4606 : 3-{4-[(2-amino-6-{4-[(3-methylphenyl)methyl]piperazin-1-yl}pyrimidin-4-yl)oxy]phenyl}-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4606 |
| Name | 3-{4-[(2-amino-6-{4-[(3-methylphenyl)methyl]piperazin-1-yl}pyrimidin-4-yl)oxy]phenyl}-2-methyl-2-phenoxypropanoic acid |
| smile | CC1=CC=CC(=C1)CN1CCN(C2=CC(=NC(=N2)N)OC2=CC=C(C=C2)CC(C(O)=O)(OC2=CC=CC=C2)C)CC1 |
| weight | 554 |
| scaffold ID | 213 |
| scaffold smile | c1ccc(CN2CCN(c3cc(Oc4ccc(CCOc5ccccc5)cc4)ncn3)CC2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4606 | 3-{4-[(2-amino-6-{4-[(3-methylphenyl)methyl]piperazin-1-yl}pyrimidin-4-yl)oxy]phenyl}-2-methyl-2-phenoxypropanoic acid | 4.46 |
Scaffold Activities Statistic