4613 : 3-[4-({2-amino-6-[4-(pyridin-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4613 |
| Name | 3-[4-({2-amino-6-[4-(pyridin-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC=C1)CC1=CC=C(C=C1)OC1=CC(N2CCN(CC2)CC2=CC=CC=N2)=NC(=N1)N |
| weight | 541 |
| scaffold ID | 1317 |
| scaffold smile | c1ccc(OCCc2ccc(Oc3cc(N4CCN(Cc5ccccn5)CC4)ncn3)cc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4613 | 3-[4-({2-amino-6-[4-(pyridin-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid | 50.0 |
Scaffold Activities Statistic