4614 : 3-[4-({2-amino-6-[4-(cyclohexylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4614 |
| Name | 3-[4-({2-amino-6-[4-(cyclohexylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC=C1)CC1=CC=C(C=C1)OC1=CC(N2CCN(CC2)CC2CCCCC2)=NC(=N1)N |
| weight | 546 |
| scaffold ID | 1318 |
| scaffold smile | c1ccc(OCCc2ccc(Oc3cc(N4CCN(CC5CCCCC5)CC4)ncn3)cc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4614 | 3-[4-({2-amino-6-[4-(cyclohexylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)phenyl]-2-methyl-2-phenoxypropanoic acid | 5.54 |
Scaffold Activities Statistic