4615 : 3-(4-{[2-amino-6-(4-benzoylpiperazin-1-yl)pyrimidin-4-yl]oxy}phenyl)-2-methyl-2-phenoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4615 |
| Name | 3-(4-{[2-amino-6-(4-benzoylpiperazin-1-yl)pyrimidin-4-yl]oxy}phenyl)-2-methyl-2-phenoxypropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC=C1)CC1=CC=C(C=C1)OC1=CC(N2CCN(C(C3=CC=CC=C3)=O)CC2)=NC(=N1)N |
| weight | 554 |
| scaffold ID | 215 |
| scaffold smile | O=C(c1ccccc1)N1CCN(c2cc(Oc3ccc(CCOc4ccccc4)cc3)ncn2)CC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4615 | 3-(4-{[2-amino-6-(4-benzoylpiperazin-1-yl)pyrimidin-4-yl]oxy}phenyl)-2-methyl-2-phenoxypropanoic acid | 50.0 |
Scaffold Activities Statistic