4669 : (2S)-2-[4-(3-chlorophenyl)piperazin-1-yl]-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4669 |
| Name | (2S)-2-[4-(3-chlorophenyl)piperazin-1-yl]-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propanoic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CCOC1=CC=C(C=C1)C[C@@H](C(O)=O)N1CCN(C2=CC=CC(=C2)Cl)CC1 |
| weight | 546 |
| scaffold ID | 159 |
| scaffold smile | c1oc(-c2ccccc2)nc1CCOc1ccc(CCN2CCN(c3ccccc3)CC2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4669 | (2S)-2-[4-(3-chlorophenyl)piperazin-1-yl]-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propanoic acid | 45.23 |
Scaffold Activities Statistic