4671 : (2S)-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}-2-[4-(2-nitrobenzenesulfonyl)piperazin-1-yl]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4671 |
| Name | (2S)-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}-2-[4-(2-nitrobenzenesulfonyl)piperazin-1-yl]propanoic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CCOC1=CC=C(C=C1)C[C@@H](C(O)=O)N1CCN(S(C2=CC=CC=C2[N+]([O-])=O)(=O)=O)CC1 |
| weight | 621 |
| scaffold ID | 1186 |
| scaffold smile | O=S(=O)(c1ccccc1)N1CCN(CCc2ccc(OCCc3coc(-c4ccccc4)n3)cc2)CC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4671 | (2S)-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}-2-[4-(2-nitrobenzenesulfonyl)piperazin-1-yl]propanoic acid | 2.16 |
Scaffold Activities Statistic