4679 : 2-[(4-chloro-6-{[4-(propan-2-yl)phenyl]amino}pyrimidin-2-yl)sulfanyl]-2-(naphthalen-1-yl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4679 |
| Name | 2-[(4-chloro-6-{[4-(propan-2-yl)phenyl]amino}pyrimidin-2-yl)sulfanyl]-2-(naphthalen-1-yl)acetic acid |
| smile | CC(C1=CC=C(C=C1)NC1=CC(=NC(=N1)SC(C1=CC=CC2=CC=CC=C12)C(O)=O)Cl)C |
| weight | 464 |
| scaffold ID | 574 |
| scaffold smile | c1ccc(Nc2ccnc(SCc3cccc4ccccc43)n2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4679 | 2-[(4-chloro-6-{[4-(propan-2-yl)phenyl]amino}pyrimidin-2-yl)sulfanyl]-2-(naphthalen-1-yl)acetic acid | 7.6 |
Scaffold Activities Statistic