4681 : 2-({4-chloro-6-[(2,3-dihydro-1H-inden-5-yl)amino]pyrimidin-2-yl}sulfanyl)-2-(naphthalen-1-yl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4681 |
| Name | 2-({4-chloro-6-[(2,3-dihydro-1H-inden-5-yl)amino]pyrimidin-2-yl}sulfanyl)-2-(naphthalen-1-yl)acetic acid |
| smile | OC(C(C1=CC=CC2=CC=CC=C12)SC1=NC(=CC(=N1)NC1=CC=C2CCCC2=C1)Cl)=O |
| weight | 462 |
| scaffold ID | 1587 |
| scaffold smile | c1ccc2c(c1)cccc2CSc1nccc(Nc2ccc3c(c2)CCC3)n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4681 | 2-({4-chloro-6-[(2,3-dihydro-1H-inden-5-yl)amino]pyrimidin-2-yl}sulfanyl)-2-(naphthalen-1-yl)acetic acid | 6.8 |
Scaffold Activities Statistic