4685 : 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)-2-(4-phenylnaphthalen-1-yl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4685 |
| Name | 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)-2-(4-phenylnaphthalen-1-yl)acetic acid |
| smile | CC1=CC=CC(=C1C)NC1=CC(=NC(=N1)SC(C1=CC=C(C2=CC=CC=C12)C1=CC=CC=C1)C(O)=O)Cl |
| weight | 526 |
| scaffold ID | 1584 |
| scaffold smile | c1ccc(Nc2ccnc(SCc3ccc(-c4ccccc4)c4ccccc34)n2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4685 | 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)-2-(4-phenylnaphthalen-1-yl)acetic acid | 4.5 |
Scaffold Activities Statistic