4805 : (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-propoxyphenyl]ethyl}phenyl)methyl]butanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4805 |
| Name | (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-propoxyphenyl]ethyl}phenyl)methyl]butanoic acid |
| smile | CCCOC1=CC(N2C(C3=CC=CC=C3C2=O)=O)=CC=C1CCC1=CC=C(C=C1)C[C@@H](C(O)=O)CC |
| weight | 486 |
| scaffold ID | 146 |
| scaffold smile | O=C1c2ccccc2C(=O)N1c1ccc(CCc2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4805 | (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-propoxyphenyl]ethyl}phenyl)methyl]butanoic acid | 5.2 |
Scaffold Activities Statistic