4812 : 2-[(1S)-1-[2-ethyl-7-methyl-5-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4812 |
| Name | 2-[(1S)-1-[2-ethyl-7-methyl-5-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]benzoic acid |
| smile | CCC1=NC2=C(C=C(N=C2N1[C@H]1CCC2=CC(C3=CC=CC=C3C(O)=O)=CC=C12)CC(C)C)C |
| weight | 454 |
| scaffold ID | 1289 |
| scaffold smile | c1nc2cccnc2n1C1CCc2cc(-c3ccccc3)ccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4812 | 2-[(1S)-1-[2-ethyl-7-methyl-5-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]benzoic acid | 0.175 |
Scaffold Activities Statistic