4821 : 5-{2-[(1S)-1-{2-cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl}-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4821 |
| Name | 5-{2-[(1S)-1-{2-cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl}-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole |
| smile | CC1=CC(=C2N=C(N(C2=N1)[C@H]1CCC2=CC(C3=CC=CC=C3C3=NN=NN3)=CC=C12)C1CC1)C |
| weight | 448 |
| scaffold ID | 1541 |
| scaffold smile | c1ccc(-c2ccc3c(c2)CCC3n2c(C3CC3)nc3cccnc32)c(-c2nnn[nH]2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4821 | 5-{2-[(1S)-1-{2-cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl}-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole | 0.762 |
Scaffold Activities Statistic