4822 : 5-{2-[(1S)-1-[5,7-dimethyl-2-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 4822 |
| Name | 5-{2-[(1S)-1-[5,7-dimethyl-2-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole |
| smile | CC(C1=NC2=C(C=C(N=C2N1[C@H]1CCC2=CC(C3=CC=CC=C3C3=NN=NN3)=CC=C12)C)C)C |
| weight | 450 |
| scaffold ID | 1288 |
| scaffold smile | c1nc2cccnc2n1C1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 4822 | 5-{2-[(1S)-1-[5,7-dimethyl-2-(propan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1H-inden-5-yl]phenyl}-1H-1,2,3,4-tetrazole | 0.295 |
Scaffold Activities Statistic