5044 : 2-methyl-2-[4-[[[4-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5044 |
| Name | 2-methyl-2-[4-[[[4-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid |
| smile | S1C(C2C=CC=C(C(F)(F)F)C=2)=NC(C)=C1C(NCC1C=CC(=CC=1)OC(C(=O)O)(C)C)=O |
| weight | 478 |
| scaffold ID | 174 |
| scaffold smile | O=C(NCc1ccccc1)c1cnc(-c2ccccc2)s1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5044 | 2-methyl-2-[4-[[[4-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid | 25.0 |
Scaffold Activities Statistic