5211 : 2-{[(1S)-1-(3-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}phenyl)ethyl](4-fluoro-3-methoxyphenoxycarbonyl)amino}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5211 |
| Name | 2-{[(1S)-1-(3-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}phenyl)ethyl](4-fluoro-3-methoxyphenoxycarbonyl)amino}acetic acid |
| smile | COC1=CC(=CC=C1F)OC(N([C@H](C1=CC=CC(=C1)OCC1=COC(C2=CC=C(C=C2)Cl)=N1)C)CC(O)=O)=O |
| weight | 555 |
| scaffold ID | 221 |
| scaffold smile | O=C(NCc1cccc(OCc2coc(-c3ccccc3)n2)c1)Oc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5211 | 2-{[(1S)-1-(3-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}phenyl)ethyl](4-fluoro-3-methoxyphenoxycarbonyl)amino}acetic acid | 0.051 |
Scaffold Activities Statistic