5333 : 2-({[3-({5-methyl-2-[4-(morpholin-4-yl)phenyl]-1,3-oxazol-4-yl}methoxy)phenyl]methyl}(4-methylphenoxycarbonyl)amino)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5333 |
| Name | 2-({[3-({5-methyl-2-[4-(morpholin-4-yl)phenyl]-1,3-oxazol-4-yl}methoxy)phenyl]methyl}(4-methylphenoxycarbonyl)amino)acetic acid |
| smile | CC1=CC=C(C=C1)OC(N(CC1=CC=CC(=C1)OCC1N=C(C2=CC=C(N3CCOCC3)C=C2)OC=1C)CC(O)=O)=O |
| weight | 572 |
| scaffold ID | 606 |
| scaffold smile | O=C(NCc1cccc(OCc2coc(-c3ccc(N4CCOCC4)cc3)n2)c1)Oc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5333 | 2-({[3-({5-methyl-2-[4-(morpholin-4-yl)phenyl]-1,3-oxazol-4-yl}methoxy)phenyl]methyl}(4-methylphenoxycarbonyl)amino)acetic acid | 0.108 |
Scaffold Activities Statistic