5377 : 2-{[(3-{[2-(4-chlorophenyl)-4-methyl-1,3-oxazol-5-yl]methoxy}phenyl)methyl](4-methylphenoxycarbonyl)amino}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5377 |
| Name | 2-{[(3-{[2-(4-chlorophenyl)-4-methyl-1,3-oxazol-5-yl]methoxy}phenyl)methyl](4-methylphenoxycarbonyl)amino}acetic acid |
| smile | CC1=CC=C(C=C1)OC(N(CC1=CC=CC(=C1)OCC1OC(C2=CC=C(C=C2)Cl)=NC=1C)CC(O)=O)=O |
| weight | 521 |
| scaffold ID | 1126 |
| scaffold smile | O=C(NCc1cccc(OCc2cnc(-c3ccccc3)o2)c1)Oc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5377 | 2-{[(3-{[2-(4-chlorophenyl)-4-methyl-1,3-oxazol-5-yl]methoxy}phenyl)methyl](4-methylphenoxycarbonyl)amino}acetic acid | 0.122 |
Scaffold Activities Statistic