5418 : 2-[(1S)-5-{2-[5-methyl-2-(3-methylphenyl)-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5418 |
| Name | 2-[(1S)-5-{2-[5-methyl-2-(3-methylphenyl)-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | CC1=CC=CC(C2=NC(=C(S2)C)CCOC2=CC=C3[C@@H](CCC3=C2)CC(O)=O)=C1 |
| weight | 408 |
| scaffold ID | 353 |
| scaffold smile | c1sc(-c2ccccc2)nc1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5418 | 2-[(1S)-5-{2-[5-methyl-2-(3-methylphenyl)-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid | 6.79 |
Scaffold Activities Statistic