5419 : 2-[(1S)-5-(2-{5-methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5419 |
| Name | 2-[(1S)-5-(2-{5-methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | CC1SC(C2=CC=C(C=C2)OC(F)(F)F)=NC=1CCOC1=CC=C2[C@@H](CCC2=C1)CC(O)=O |
| weight | 478 |
| scaffold ID | 353 |
| scaffold smile | c1sc(-c2ccccc2)nc1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 5419 | 2-[(1S)-5-(2-{5-methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid | 7.94 |
Scaffold Activities Statistic