5443 : 2-[4-[ethyl-(1-phenyl-2-phenylmethoxyethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 46)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5443 |
| Name | 2-[4-[ethyl-(1-phenyl-2-phenylmethoxyethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 46) |
| smile | CCN(C(C1=CC=CC=C1)COCC1=CC=CC=C1)C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1 |
| weight | 497 |
| scaffold ID | 382 |
| scaffold smile | c1ccc(COCC(Nc2ccccc2)c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5443 | 2-[4-[ethyl-(1-phenyl-2-phenylmethoxyethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 46) | 0.6 |
Scaffold Activities Statistic