5451 : 2-[4-[ethyl-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl]amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 20)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5451 |
| Name | 2-[4-[ethyl-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl]amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 20) |
| smile | CCN(C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)CC1=C(C)OC(C2=CC(C(F)(F)F)=CC=C2)=N1 |
| weight | 526 |
| scaffold ID | 250 |
| scaffold smile | c1oc(-c2ccccc2)nc1CNc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5451 | 2-[4-[ethyl-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl]amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 20) | 0.06 |
Scaffold Activities Statistic