5457 : 2-[5-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrazin-2-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5457 |
| Name | 2-[5-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrazin-2-yl]acetic acid |
| smile | CCCC1=C(OCCCN(C2=NC=C(CC(O)=O)N=C2)C)C=CC2=C1ON=C2C(F)(F)F |
| weight | 452 |
| scaffold ID | 840 |
| scaffold smile | c1noc2cc(OCCCNc3cnccn3)ccc12 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5457 | 2-[5-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrazin-2-yl]acetic acid | 0.15 |
Scaffold Activities Statistic