5469 : 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5469 |
| Name | 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid |
| smile | OC(CC1=CC=CC2=C1C=CC=C2NCC1=CC(C2=C3C=CC=C(C(F)(F)F)C3=NC=C2CC2=CC=CC=C2)=CC=C1)=O |
| weight | 577 |
| scaffold ID | 548 |
| scaffold smile | c1ccc(Cc2cnc3ccccc3c2-c2cccc(CNc3cccc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5469 | 2-{5-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]naphthalen-1-yl}acetic acid | 0.355 |
Scaffold Activities Statistic