5483 : 2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indole-5-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5483 |
| Name | 2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indole-5-carboxylic acid |
| smile | CCCC1=C(OCCCN2C(CC3=C2C=CC(C(O)=O)=C3)=O)C=CC2=C1ON=C2C(F)(F)F |
| weight | 462 |
| scaffold ID | 119 |
| scaffold smile | O=C1Cc2ccccc2N1CCCOc1ccc2cnoc2c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5483 | 2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indole-5-carboxylic acid | 4.4 |
Scaffold Activities Statistic